What people who live to 100 years old have in common, according to science

Published in Science and Technology on Thursday, August 14th 2025 at 7:47 GMT by Fox News
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Studies show that centenarians, people who live to 100, accumulate health conditions more slowly and have a lower disease burden compared to shorter-lived individuals.

Secrets to a Long Life: What Centenarians Have in Common, According to Science

In an era where life expectancy continues to rise in many parts of the world, the quest to understand what allows some people to reach the remarkable age of 100 or beyond has captivated scientists, researchers, and the general public alike. Centenarians—those who live to 100 years or older—represent a small but fascinating subset of the population. While genetics undoubtedly play a role, emerging scientific studies suggest that lifestyle, environment, and daily habits are key factors that many of these long-lived individuals share. Drawing from global research, including insights from the famous Blue Zones—regions like Okinawa in Japan, Sardinia in Italy, Nicoya in Costa Rica, Icaria in Greece, and Loma Linda in California—experts have identified common threads that weave through the lives of those who defy the odds and thrive into their second century.

One of the most prominent commonalities among centenarians is their approach to diet. Science consistently points to a plant-based, nutrient-rich eating pattern as a cornerstone of longevity. In Blue Zones, for instance, diets are predominantly composed of vegetables, fruits, whole grains, beans, and nuts, with minimal processed foods or sugars. Okinawans, known for having one of the highest concentrations of centenarians, follow the principle of "hara hachi bu," which means eating until they are 80% full, effectively practicing calorie restriction without deprivation. This mirrors findings from studies like the Adventist Health Study, which tracks the habits of Seventh-day Adventists in Loma Linda, many of whom are vegetarians and live significantly longer than average. Research published in journals such as Nature and the Journal of the American Geriatrics Society supports this, showing that diets low in animal proteins and high in fiber reduce inflammation, lower cholesterol, and promote healthy gut microbiomes—all of which combat age-related diseases like heart disease, diabetes, and cancer.

Beyond diet, physical activity emerges as another universal trait, but not in the form of intense gym workouts. Instead, centenarians often engage in natural, low-intensity movement integrated into daily life. In Sardinia, shepherds walk miles over hilly terrain while tending flocks, while in Nicoya, people perform manual labor like farming or household chores well into old age. This aligns with data from the World Health Organization and longitudinal studies, which indicate that consistent, moderate activity—such as gardening, walking, or yoga—enhances cardiovascular health, maintains muscle mass, and boosts mental well-being. A study from the University of California, San Diego, found that older adults who incorporate daily movement reduce their risk of frailty and cognitive decline, key barriers to reaching 100.

Social connections and a sense of community also stand out as vital elements. Centenarians rarely live in isolation; they are embedded in tight-knit families and social networks that provide emotional support and purpose. In Okinawa, the concept of "moai"—lifelong groups of friends who meet regularly—fosters belonging and reduces stress. Psychological research, including work from Harvard's Grant Study, one of the longest-running studies on human development, underscores that strong relationships are the strongest predictor of long life, even more so than cholesterol levels or exercise. These bonds help buffer against loneliness, which has been linked to increased mortality risk in numerous epidemiological studies. Moreover, many centenarians report having a "ikigai" or reason for being—a purpose that motivates them daily, whether it's family, work, or hobbies. This sense of purpose correlates with lower rates of depression and better immune function, as evidenced by research in The Lancet.

Stress management is another shared habit, often achieved through simple, mindful practices. In Blue Zones, routines like napping, prayer, or communal downtime help mitigate chronic stress, which accelerates cellular aging through mechanisms like telomere shortening. Scientific investigations, such as those from the National Institute on Aging, reveal that centenarians tend to have resilient stress responses, possibly due to genetic factors but also lifestyle choices like meditation or religious faith. For example, the devout Adventists in Loma Linda observe a weekly Sabbath of rest, which researchers believe contributes to their extended lifespans by promoting recovery and reducing cortisol levels.

Genetics, while not entirely controllable, do factor in. Studies of centenarians' DNA, including the New England Centenarian Study, have identified variants in genes like FOXO3, which regulate insulin signaling and cellular repair, appearing more frequently in those who live exceptionally long. However, experts emphasize that genes account for only about 20-30% of longevity, with the rest influenced by environment and behavior. This is supported by twin studies showing that even identical twins with the same genetics can have vastly different lifespans based on lifestyle.

Environmental factors also play a role. Many centenarians hail from areas with clean air, access to fresh produce, and low pollution—conditions that minimize exposure to toxins that hasten aging. In Icaria, the Mediterranean climate and island lifestyle encourage outdoor living and fresh, local foods. Climate and geography thus indirectly support the habits that lead to longevity.

Interestingly, centenarians often share optimistic outlooks and resilience in the face of adversity. Psychological profiles from studies like the Georgia Centenarian Study highlight traits such as adaptability, humor, and a positive attitude, which help them navigate life's challenges without succumbing to despair. This mental fortitude is linked to better health outcomes, including stronger immune systems and lower inflammation.

While not all centenarians follow every one of these patterns perfectly, the convergence of these elements—healthy eating, natural movement, social ties, purpose, stress reduction, and supportive environments—paints a clear picture of what science says promotes extreme longevity. Researchers caution that there's no single "magic bullet," but adopting even a few of these habits can significantly increase one's chances of a longer, healthier life. As global populations age, these insights offer valuable lessons for public health initiatives, encouraging societies to foster communities that prioritize well-being over mere survival. By emulating the ways of centenarians, individuals everywhere can aim not just for more years, but for more vibrant, fulfilling ones. (Word count: 912)

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What people who live to 100 years old have in common, according to science

Secrets to a Long Life: What Centenarians Have in Common, According to Science