Brain Reset: One Molecular Switch Could Silence Alzheimer's and Parkinson's

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[ Thu, May 29th ]: CNN

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Wed, May 28, 2025

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[ Wed, May 28th ]: Nature

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Brain Reset: One Molecular Switch Could Silence Alzheimer's and Parkinson's

//science-technology.news-articles.net/content/2 .. h-could-silence-alzheimer-s-and-parkinson-s.html

Published in Science and Technology on Thursday, May 29th 2025 at 19:22 GMT by SciTechDaily

One scientist may have cracked the code to curing Alzheimer's and Parkinson's using a single molecular switch.

The article from SciTechDaily discusses a groundbreaking study from the University of Colorado Anschutz Medical Campus, revealing that a single molecular switch could potentially silence neurodegenerative diseases like Alzheimer's and Parkinson's. The research, published in the journal Science Advances, focuses on the protein KCNJ3, which is overexpressed in the brains of individuals with these diseases. By using antisense oligonucleotides (ASOs), researchers were able to silence the KCNJ3 gene in mouse models, leading to a significant reduction in neurodegeneration and an improvement in cognitive function. This approach offers a promising new therapeutic strategy for treating these debilitating conditions by targeting the root cause at the molecular level.

Read the Full SciTechDaily Article at:
[ https://scitechdaily.com/brain-reset-one-molecular-switch-could-silence-alzheimers-and-parkinsons/ ]

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Brain Reset: One Molecular Switch Could Silence Alzheimer's and Parkinson's