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AI-based platform designs peptides to target 'undruggable' proteins


Published on 2025-01-29 12:02:27 - MSN
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  • Biomedical engineers at Duke University have developed an AI-based platform that designs short proteins, termed peptides, capable of binding and destroying previously undruggable disease-causing proteins.

The article from MSN discusses a groundbreaking development in biotechnology where an AI-based platform has been designed to create peptides that can target proteins previously considered "undruggable." These proteins are typically involved in diseases like cancer, Alzheimer's, and various genetic disorders but have been difficult to target with traditional small molecule drugs due to their structure or location within the cell. The AI platform, developed by researchers, uses machine learning algorithms to predict and design peptides that can effectively bind to these challenging protein targets. This approach not only opens up new avenues for drug discovery but also significantly reduces the time and cost associated with developing new treatments. The platform's success in designing effective peptides has been validated through experiments, showing promising results in targeting these previously inaccessible proteins, potentially revolutionizing treatment options for numerous diseases.

Read the Full MSN Article at:
[ https://www.msn.com/en-us/technology/biotechnology/ai-based-platform-designs-peptides-to-target-undruggable-proteins/ar-AA1y4nAA ]
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