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SANTA CLARA, Calif. & MAASTRICHT, Netherlands--([ BUSINESS WIRE ])--Agilent Technologies Inc. (NYSE:A) and the Agilent Technologies Foundation today announced that Dr. Chris Evelo and the department of bioinformatics at Maastricht University are the recipients of an Agilent Thought Leader Award supporting development of software to integrate different types of biological data. The goal of this award is to help accelerate breakthroughs in disease research by facilitating integrative systems biology approaches.

"Our work is aimed at achieving better understanding of large biological datasets"

The Evelo Lab helped develop WikiPathways.org as a community-curated platform for structuring multi-omics data and the associated open-access pathway analysis tool PathVisio. The Agilent Thought Leader Award will fund development of tools for visualizing metabolite fluxes using PathVisio. The goal is to make modeling results much more accessible to biologists and easier for them to interpret.

aOur work is aimed at achieving better understanding of large biological datasets,a Dr. Evelo said. aFor this we need the context of biology that we already know and the integration of many types of data. This grant allows us to use existing representation of biological pathways to view flux data from models. That will model results which are much easier to interpret than abstract graphs.a

aWeare very pleased to help fund the work at the Evelo Lab, as it closely aligns with a major initiative at Agilent: pursuing breakthroughs in biology and medicine through the ability to integrate diverse life science datasets,a said John Fjeldsted, Ph.D., vice president and general manager of Agilentas LC/MS business. aBioinformatics software is still catching up to researchersa abilities to generate data, and we feel that a wide segment of the science community will benefit from this work.a

The tools that will be developed in Dr. Eveloas lab will also help researchers who develop flux modeling approaches to improve their models and facilitate their distribution. Basically, these efforts will build a bridge between biologists and metabolic modelers, enabling both communities to better leverage each othersa insights.

Development of a new application for gene ontologies is also part of the project. Presently, pathway analysis and gene ontology analysis are complementary but separate approaches. The new application will enrich integrated biology research by using gene ontology data currently available only for genes and extending it to pathway and metabolite analysis.

About Agilent Technologies

Agilent Technologies Inc. (NYSE: A) is the worldas premier measurement company and a technology leader in chemical analysis, life sciences, electronics and communications. The companyas 18,700 employees serve customers in more than 100 countries. Agilent had net revenues of $6.6 billion in fiscal 2011. Information about Agilent is available at [ www.agilent.com ].

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